SLC39A13
Zinc deficiency
0.210
Biomarker
RGD
Over-expression of Zip-13 mRNA in kidney and lung during dietary zinc deficiency in Wistar rats.
20859692 2011
×
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
Zinc deficiency
0.200
Biomarker
RGD
The influence of gestational zinc deficiency on the fetal insulin-like growth factor axis in the rat.
20404036 2010
×
Entrez Id: 5189
Gene Symbol: PEX1
PEX1
Zellweger Syndrome
0.800
Biomarker
MGD
×
Entrez Id: 8799
Gene Symbol: PEX11B
PEX11B
Zellweger Syndrome
0.510
Biomarker
MGD
×
Entrez Id: 9896
Gene Symbol: FIG4
FIG4
Yunis Varon syndrome
0.980
Biomarker
MGD
Yunis-Varón syndrome is caused by mutations in FIG4, encoding a phosphoinositide phosphatase.
23623387 2013
×
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
XFE Progeroid Syndrome
0.200
Biomarker
MGD
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.
17183314 2006
×
Entrez Id: 5429
Gene Symbol: POLH
POLH
Xeroderma pigmentosum, variant type
0.940
Biomarker
MGD
Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse.
15824086 2005
×
Entrez Id: 5429
Gene Symbol: POLH
POLH
Xeroderma pigmentosum, variant type
0.940
Biomarker
MGD
Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice.
16397220 2006
×
Entrez Id: 5429
Gene Symbol: POLH
POLH
Xeroderma pigmentosum, variant type
0.940
Biomarker
MGD
Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification.
15939880 2005
×
Entrez Id: 2073
Gene Symbol: ERCC5
ERCC5
Xeroderma Pigmentosum, Type G-Cockayne Syndrome
0.300
Biomarker
MGD
To test the hypothesis that the CS phenotype, with characteristics such as growth retardation and a short life span in XPG/CS patients, results from C-terminal truncations, we constructed mutants with C-terminal truncations in mouse XPG (Xpg) (from residue D811 to the stop codon [XpgD811stop] and deletion of exon 15 [Xpg Delta ex15]).
15082767 2004
×
Entrez Id: 2073
Gene Symbol: ERCC5
ERCC5
Xeroderma Pigmentosum, Type G-Cockayne Syndrome
0.300
Biomarker
MGD
Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene.
10022922 1999
×
Entrez Id: 2072
Gene Symbol: ERCC4
ERCC4
XERODERMA PIGMENTOSUM, TYPE F/COCKAYNE SYNDROME
0.300
Biomarker
MGD
Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF.
14729965 2004
×
Entrez Id: 2073
Gene Symbol: ERCC5
ERCC5
Xeroderma pigmentosum, group G
1.000
Biomarker
MGD
The known XPG protein function as the 3' nuclease in NER, however, cannot explain the development of CS in certain XP-G patients.
10022922 1999
×
Entrez Id: 2073
Gene Symbol: ERCC5
ERCC5
Xeroderma pigmentosum, group G
1.000
Biomarker
MGD
The control mice, in which one-half of Xpg genomic DNA fragment was replaced with a normal Xpg cDNA fragment, had a normal growth rate, a normal life span, normal sensitivity to UV light, and normal DNA repair ability, indicating that the Xpg gene partially replaced with the normal cDNA fragment retained normal functions.
15082767 2004
×
Entrez Id: 2072
Gene Symbol: ERCC4
ERCC4
Xeroderma pigmentosum, group F
1.000
Biomarker
MGD
Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF.
14729965 2004
×
Entrez Id: 2071
Gene Symbol: ERCC3
ERCC3
Xeroderma pigmentosum, group B
1.000
Biomarker
MGD
An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair.
19114557 2009
×
Entrez Id: 7507
Gene Symbol: XPA
XPA
Xeroderma pigmentosum, group A
1.000
Biomarker
MGD
The data suggest that the XPA gene-deficient mice may be a useful model of human XPA , because the responses to UV radiation in the mice were very similar to those in the patients with XPA .
8751968 1996
×
Entrez Id: 7507
Gene Symbol: XPA
XPA
Xeroderma pigmentosum, group A
1.000
Biomarker
MGD
Ultraviolet radiation-induced suppression of natural killer cell activity is enhanced in xeroderma pigmentosum group A (XPA) model mice.
10383746 1999
×
Entrez Id: 7507
Gene Symbol: XPA
XPA
Xeroderma pigmentosum, group A
1.000
Biomarker
MGD
Possible involvement of enhanced prostaglandin E2 production in the photosensitivity in xeroderma pigmentosum group A model mice.
10651981 2000
×
Entrez Id: 7507
Gene Symbol: XPA
XPA
Xeroderma pigmentosum, group A
1.000
Biomarker
MGD
Impaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice.
18790090 2008
×
Entrez Id: 7507
Gene Symbol: XPA
XPA
Xeroderma pigmentosum, group A
1.000
Biomarker
MGD
Mice deficient in the nucleotide excision repair gene XPA have elevated sensitivity to benzo[a]pyrene induction of lung tumors.
10837020 2000
×
Entrez Id: 7507
Gene Symbol: XPA
XPA
Xeroderma pigmentosum, group A
1.000
Biomarker
MGD
High incidence of ultraviolet-B-or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group A gene.
7675085 1995
×
Entrez Id: 1643
Gene Symbol: DDB2
DDB2
XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP E
1.000
Biomarker
MGD
Moreover, DDB2 is mutated in the repair-deficiency disease xeroderma pigmentosum (Group E ).
15558025 2005
×
Entrez Id: 1643
Gene Symbol: DDB2
DDB2
XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP E
1.000
Biomarker
MGD
Mutations in the human DDB2 gene give rise to xeroderma pigmentosum group E , a disease characterized by increased skin tumorigenesis in response to UV-irradiation.
14769931 2004
×
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
Xeroderma Pigmentosum, Complementation Group D
1.000
Biomarker
MGD
An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria.
16904611 2006